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Biostatistics (Spring 2012)

Course code : EBIOS-U1
ECTS Credits : 5 Status : Optional
Revised : 22/12 2011 Written : 22/12 2011
Placement : 5. - 7. semester Hours per week : 4
Length : 1 semester Teaching Language : English if English students are present

Objective : Based on a selection of statistical problems from the medical- and biological area, the course presents a selection of widely used models and methods.

Having passed the course, the student will be able to accomplish the following, within the areas shown below:

Apply fundamental statistical models for a selection of medical- og biological problems.
Carry out descriptive analysis of data including applying visualization methods.
Estimating linear and logistic models using regression and correlation.
Compare models based on small samples sizes.
Formulate a quality control problem for given sample sizes and probability models.
Use the language R as a statistical analysis tool.
Principal Content : Probability; discrete and continuous stochastic variables; descriptive analysis of data including visualization; binomial, uniform and normal distribution; sample mean and standard error; confidence intervals; testing a hypothesis; significance test; the t- distribution; linear and logistic regression including model verification; least squares; non-parametric tests; clinical measurements; mortality statistics; quality control.
Teaching method : Sessions in class with active participation by the students. The time will be divi-ded between lectures and the students solving problems, including solving statis-tical problems in the open source language R.
Required prequisites : Documented knowledge corresponding to the first year mathematics level.
Recommended prerequisites : -
Relations : -
Type of examination : Oral examination
External examiner : External
Marking : 7 step scale
Remarks : 7 step scale

3 steps of this marking scale are described as follows:

12 is given for the excellent presentation, which completely fulfills the course
goals, with no or very few errors of marginal importance.

7 is given for the average presentation, which fulfills the course goals, with some
errors in the presentation.

02 is given for the minimum acceptable presentation, which fulfills the course goals.
Teaching material : Martin Bland “An Introduction to Medical Statistics” Third Ed.
Oxford University Press, 2009.
Responsible teacher : John Aasted Sørensen , jaas@dtu.dk